Invitrogen™ APC11 Monoclonal Antibody (OTI1F2)

Catalog No.	Quantity
PIMA526262	100 μL

Catalog No. PIMA526262 Supplier Invitrogen™ Supplier No. MA526262

Description

Mouse Monoclonal Antibody

APC11 Monoclonal Antibody for Western Blot, IHC (P)

Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProt].

Specifications

• Antigen: APC11
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI1F2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ANAPC11
• Gene Accession No.: Q9NYG5
• Gene Alias: 1110011I19Rik; Anapc11; anaphase promoting complex subunit 11; anaphase promoting complex subunit 11 (yeast APC11 homolog); anaphase promoting complex subunit 11 homolog; anaphase-promoting complex subunit 11; APC11; APC11 anaphase promoting complex subunit 11 homolog; Apc11p; Cyclosome subunit 11; hepatocellular carcinoma-associated RING finger protein; HSPC214; R75218; RGD1561880
• Gene Symbols: ANAPC11
• Host Species: Mouse
• Immunogen: Full length human recombinant protein of ANAPC11 produced in HEK293T cell.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51529
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1