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Invitrogen™ APC11 Polyclonal Antibody
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Catalog No. PIPA555709
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100 μL
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PIPA555709 100 μL
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Catalog No. PIPA555709 Supplier Invitrogen™ Supplier No. PA555709
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ANDENCGICR MAFNGCCPDC PLHGESISRC LGWCPQPVPV LGGRAHPQVP INTASPTPGQ HTGSLMSREE SSRSPDPTPP AL Highest antigen sequence identity to the following orthologs: Mouse - 28%, Rat - 28%.

Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC11
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ANAPC11
Gene Accession No. Q9NYG5
Gene Alias 1110011I19Rik; Anapc11; anaphase promoting complex subunit 11; anaphase promoting complex subunit 11 (yeast APC11 homolog); anaphase promoting complex subunit 11 homolog; anaphase-promoting complex subunit 11; APC11; APC11 anaphase promoting complex subunit 11 homolog; Apc11p; Cyclosome subunit 11; hepatocellular carcinoma-associated RING finger protein; HSPC214; R75218; RGD1561880
Gene Symbols ANAPC11
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human APC11. Recombinant protein control fragment (Product #RP-93302).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51529
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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