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Invitrogen™ APC15 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA557736
Description
Immunogen sequence: PSLFPRVTET LWFNLDRPCV EETELQQQEQ QHQAWLQSIA EKDNNLVPIG KPASEHYDDE EEED Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
Specifications
APC15 | |
Polyclonal | |
Unconjugated | |
Anapc15 | |
3200002M19Rik; 6330414C15Rik; Anapc15; anaphase promoting complex subunit 15; anaphase prompoting complex C subunit 15; anaphase-promoting complex subunit 15; APC15; C11orf51; C15H11orf51; C21H11orf51; HSPC020; hypothetical protein LOC505356; protein HSPC020 homolog; RGD1311634; uncharacterized protein C11orf51 homolog; Unknown (protein for MGC:153425); zgc:153425 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
25906 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.3 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P60006 | |
Anapc15 | |
Recombinant protein corresponding to Human APC15. Recombinant protein control fragment (Product #RP-97313). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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