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Invitrogen™ APC4 Polyclonal Antibody
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Catalog No. PIPA558372
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100 μL
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PIPA558372 100 μL
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Catalog No. PIPA558372 Supplier Invitrogen™ Supplier No. PA558372
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VTVVLKDTVG REGRDRLLVQ LPLSLVYNSE DSAEYQFTGT YSTRLDEQCS AIPTRTMHFE KHWRLLESMK AQYVAGNGFR KVSCVLSSNL RHV Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ANAPC4
Gene Accession No. Q9UJX5
Gene Alias 2610306D21Rik; ANAPC4; anaphase promoting complex subunit 4; anaphase-promoting complex subunit 4; APC4; cyclosome subunit 4; D5Ertd249e
Gene Symbols ANAPC4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human APC4. Recombinant protein control fragment (Product #RP-96599).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29945
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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