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Invitrogen™ APC5 Polyclonal Antibody
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Catalog No. PIPA520946
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100 μg
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Catalog No. Quantity
PIPA520946 100 μg
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Catalog No. PIPA520946 Supplier Invitrogen™ Supplier No. PA520946
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human kidney tissue lysate. PA5-20946 can be used with blocking peptide PEP-1060.

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome, a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein, compared to isoform a.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC5
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Anapc5
Gene Accession No. A1L1K3, Q8BTZ4, Q9UJX4
Gene Alias 2510006G12Rik; AA408751; AA536819; AA986414; ANAPC5; anaphase promoting complex subunit 5; anaphase-promoting complex subunit 5; Anpc5; APC5; cyclosome subunit 5; MNCb-2778
Gene Symbols Anapc5
Host Species Rabbit
Immunogen A 17 amino acid peptide near the center of human APC5.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 288671, 51433, 59008
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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