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APC5 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988006
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50-198-8006 100 μL
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Catalog No. 50-198-8006 Supplier Bioss Supplier No. BS7778R
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Description

Rabbit Polyclonal Antibody

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome , a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein , compared to isoform a.

Specifications

Antigen APC5
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Anapc5
Gene Accession No. Q9UJX4
Gene Alias 2510006G12Rik; AA408751; AA536819; AA986414; Anapc5; anaphase promoting complex subunit 5; Anaphase-promoting complex subunit 5; Anpc5; APC5; Cyclosome subunit 5; MNCb-2778
Gene Symbols Anapc5
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human APC5.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51433
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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