Invitrogen™ APC6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121073

Catalog No. PIPA5121073

Description

Positive test controls include: Jurkat, HepG2, HeLa, A-549, Mouse brain, Mouse ovary, Rat brain. The target is usually found in the following locations: Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle. Immunogen sequence: MLYIGLEYGL TNNSKLAERF FSQALSIAPE DPFVMHEVGV VAFQNGEWKT AEKWFLDALE KIKAIGNEVT VDKWEPLLNN LGHVCRKLKK YAEALDYHRQ ALVLIPQNAS TYSAIGYIHS LMGNFENAVD YFHTALGLRR DDTFSVTMLG HCIEMYIGDS EAYIGADIKD KLKCYDFDVH TMKTLKNIIS PPWDFREFEV EKQTAEETGL TPLETSRKTP DSRPSLEETF EIEMNESDMM LETSMSDHST.

The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Specifications

• Antigen: APC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cdc16
• Gene Alias: 2700071J12Rik; 2810431D22Rik; ANAPC6; Anaphase-promoting complex subunit 6; anaphase-promoting complex, subunit 6; APC6; Cdc16; CDC16 cell division cycle 16; CDC16 cell division cycle 16 homolog; CDC16 homolog; CDC16Hs; cell division cycle 16; cell division cycle 16 homolog; cell division cycle protein 16 homolog; CUT9; Cyclosome subunit 6; RP11-569D9.4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290875, 69957, 8881
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13042, Q8R349
• Gene Symbols: Cdc16
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 371-620 of human CDC16 (NP_003894.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov