APC7 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-2574	Bethyl Laboratories, Inc IHC00706T	10 μL
50-157-2573	Bethyl Laboratories, Inc IHC00706	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, Chicken, Turkey, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Monkey,

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.

Specifications

• Antigen: APC7
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: APC7, anaphase-promoting complex subunit 7; cyclosome subunit 7
• Immunogen: Between 515 and 565
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: ANAPC7

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q9UJX3, Q9WVM3
• Gene ID (Entrez): 51434, 56317
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody