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  5. Tocris Bioscience™ Apcin

Tocris Bioscience™ Apcin
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Catalog No. 574710
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Cdc20 inhibitor; inhibits Cdc20-substrate interaction

Apcin is a Cdc20 inhibitor; inhibits Cdc20-substrate interaction. Blocks substrate-mediated Cdc20 loading onto the anaphase-promoting complex (APC). Inhibits APC-dependent ubiquitylation. Prolongs mitotic duration in RPE1 cells in combination with proTAME (prodrug of TAME (Cat.No. 4506)) in vitro.

Specifications

Chemical Name or Material 3-(2-Methyl-5-nitroimidazol-1-yl)-N-(2,2,2-trichloro-1-phenylaminoethyl)propionamide
CAS 300815-04-7
Quantity 10 mg
Target Ubiquitin Ligase (E3) Inhibitors
Molecular Formula C13H14Cl3N7O4
Formula Weight 438.65
Purity >98%
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