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APCL/APC2 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody
Supplier: Bioss BS12485R

Description
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. Like APC11, APC2 contains cullin and RING finger domains that are thought to be important in regulating ubiquitination activity.Specifications
APCL/APC2 | |
Polyclonal | |
Unconjugated | |
APC2 | |
adenomatosis polyposis coli 2; adenomatous polyposis coli like; Adenomatous polyposis coli protein 2; Adenomatous polyposis coli protein-like; AI852447; APC2; APC2, WNT signaling pathway regulator; APCL; APC-like; R75424 | |
Rabbit | |
Protein A | |
RUO | |
10297 | |
-20°C | |
Liquid |
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
1 μg/mL | |
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH | |
O95996 | |
APC2 | |
KLH conjugated synthetic peptide derived from human APCL/APC2. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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