Invitrogen™ APEH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543138

Catalog No. PIPA543138

Description

Peptide sequence: GSTGFGQDSI LSLPGNVGHQ DVKDVQFAVE QVLQEEHFDA SHVALMGGSH Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 92%.

APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.

Specifications

• Antigen: APEH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APEH
• Gene Alias: AARE; ACPH; Acylamino-acid-releasing enzyme; acylamino-acid-releasing enzyme-like; acylaminoacyl-peptidase; acylaminoacyl-peptide hydrolase; acylpeptide hydrolase; Acyl-peptide hydrolase; Apeh; APH; cb5; D3F15S2; D3S48E; DNF15S2; LOW QUALITY PROTEIN: acylamino-acid-releasing enzyme; acylamino-acid-releasing enzyme; MGC2178; N-acylaminoacyl peptide hydrolase; N-acylaminoacyl-peptide hydrolase; OPH; Oxidized protein hydrolase; sb:cb5; wu:fi37d02
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 327
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P13798
• Gene Symbols: APEH
• Immunogen: Synthetic peptide directed towards the middle region of human APEH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG