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Invitrogen™ APEH Polyclonal Antibody
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Catalog No. PIPA583099
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PIPA583099 100 μL
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Catalog No. PIPA583099 Supplier Invitrogen™ Supplier No. PA583099
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Rabbit Polyclonal Antibody

Immunogen sequence: RQYLVFHDGD SVVFAGPAGN SVETRGELLS RESPSGTMKA VLRKAGGTGP GEEKQFLEVW EKNRKLKSFN LSALEKHGPV YEDDCFGC Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 97%.

APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APEH
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene APEH
Gene Accession No. P13676, P13798
Gene Alias AARE; ACPH; Acylamino-acid-releasing enzyme; acylamino-acid-releasing enzyme-like; acylaminoacyl-peptidase; acylaminoacyl-peptide hydrolase; acylpeptide hydrolase; Acyl-peptide hydrolase; Apeh; APH; cb5; D3F15S2; D3S48E; DNF15S2; LOW QUALITY PROTEIN: acylamino-acid-releasing enzyme; acylamino-acid-releasing enzyme; MGC2178; N-acylaminoacyl peptide hydrolase; N-acylaminoacyl-peptide hydrolase; OPH; Oxidized protein hydrolase; sb:cb5; wu:fi37d02
Gene Symbols APEH
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human APEH. Recombinant protein control fragment (Product #RP-95870).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24206, 327
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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