Invitrogen™ APEH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589251

Catalog No. PIPA589251

Description

Immunogen sequence: MERQVLLSEP EEAAALYRGL SRQPALSAAC LGPEVTTQYG GQYRTVHTEW TQRDLERMEN IRFCRQYLVF HDGDSVVFAG PAGNSVETRG ELLSRESPSG TMKAVLRKAG GTGPGEEKQF LEVWEKNRKL KSFNLSALEK HGPVYEDDCF GCLSWSHSET HLLYVAEKKR PKAESFFQTK ALDVSASDDE IARLKKPDQA IKGDQFVFYE DWGENMVSKS IPVLCVLDVE SGNISVLEGV PENVSPGQAF WAPGDAGVVF; Positive Samples: SW480, Jurkat, Mouse liver, Mouse kidney, Mouse small intestine, Rat bone marrow; Cellular Location: Cytoplasm.

APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.

Specifications

• Antigen: APEH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APEH
• Gene Alias: AARE; ACPH; Acylamino-acid-releasing enzyme; acylamino-acid-releasing enzyme-like; acylaminoacyl-peptidase; acylaminoacyl-peptide hydrolase; acylpeptide hydrolase; Acyl-peptide hydrolase; Apeh; APH; cb5; D3F15S2; D3S48E; DNF15S2; LOW QUALITY PROTEIN: acylamino-acid-releasing enzyme; acylamino-acid-releasing enzyme; MGC2178; N-acylaminoacyl peptide hydrolase; N-acylaminoacyl-peptide hydrolase; OPH; Oxidized protein hydrolase; sb:cb5; wu:fi37d02
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 235606, 24206, 327
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P13676, P13798, Q8R146
• Gene Symbols: APEH
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human APEH (NP_0016313).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG