Invitrogen™ Apelin Receptor Recombinant Rabbit Monoclonal Antibody (5H5L9)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 702069

Catalog No. PI702069

Description

This antibody is predicted to react with Monkey, Rabbit, Horse and Dog Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

APLNR (Apelin Receptor) is a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Specifications

• Antigen: Apelin Receptor
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: P35414, Q9WV08
• Gene Symbols: Aplnr
• Immunogen: Peptides corresponding to Human APLNR (aa 6-20, 52-66).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: 5H5L9
• Conjugate: Unconjugated
• Gene: Aplnr
• Gene Alias: AGTRL1; angiotensin II receptor-like 1; angiotensin receptor-like 1; Apelin receptor; APJ; APJ (apelin) receptor; APJ receptor; APJR; Aplnr; B78; G protein-coupled receptor APJ; GPCR34; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11; HG11 orphan receptor; MSR; msr/apj
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 187, 23796
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid