APEX1 Mouse anti-Human, Clone: OTI2A4, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA800333

Catalog No. 50-167-8255

Description

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Specifications

• Antigen: APEX1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P27695
• Gene Symbols: APEX1
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-242 of human APEX1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2A4
• Conjugate: Unconjugated
• Gene: APEX1
• Gene Alias: APE, APE1, APEN, APEX, APX, HAP1, REF1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 328
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid