APEX1 Mouse anti-Human, Clone: OTI2A4, liquid, TrueMAB™

Catalog No.	Quantity
50-167-8255	100 μL

Catalog No. 50-167-8255 Supplier OriGene Supplier No. TA800333

Description

Mouse Monoclonal Antibody

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Specifications

• Antigen: APEX1
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2A4
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: APEX1
• Gene Accession No.: P27695
• Gene Alias: APE, APE1, APEN, APEX, APX, HAP1, REF1
• Gene Symbols: APEX1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-242 of human APEX1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 328
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a