APEX2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7356	100 μL

Catalog No. 50-198-7356 Supplier Bioss Supplier No. BS6587R

Description

Rabbit Polyclonal Antibody

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER).

Specifications

• Antigen: APEX2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: APEX2
• Gene Accession No.: Q9UBZ4
• Gene Alias: AP endonuclease 2; AP endonuclease XTH2; APE2; APEX nuclease (apurinic/apyrimidinic endonuclease) 2; APEX nuclease 2; APEX nuclease-like 2; APEX2; APEXL2; apurinic/apyrimidinic endodeoxyribonuclease 2; apurinic/apyrimidinic endonuclease-like 2; Apurinic-apyrimidinic endonuclease 2; DNA-(apurinic or apyrimidinic site) lyase 2; RP5-884M20.3; XTH2; ZGRF2; zinc finger, GRF-type containing 2
• Gene Symbols: APEX2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human APEX2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 27301
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG