Invitrogen™ API5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555354

Catalog No. PIPA555354

Description

Immunogen sequence: TVEELYRNYG ILADATEQVG QHKDAYQVIL DGVKGGTKEK RLAAQFIPKF FKHFPELADS AINAQLDLCE DEDVSIRRQA IKELPQFATG ENLPRVADIL TQLLQTDDSA EFNLVN Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: API5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: API5
• Gene Alias: AAC11; AAC-11; AI196452; antiapoptosis clone 11 protein; API5; API-5; Apoptosis inhibitor 5; cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; fibroblast growth factor 2-interacting factor 2; FIF; FIF C1; MIG8; migration-inducing protein MIG8; Protein XAGL
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11800, 362170, 8539
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O35841, Q9BZZ5
• Gene Symbols: API5
• Immunogen: Recombinant protein corresponding to Human API5. Recombinant protein control fragment (Product #RP-92069).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG