Invitrogen™ API5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578793

Catalog No. PIPA578793

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Cardiac Muscle TissueRat Brain Tissue, Rat Testis Tissue, Rat Placenta Tissue, MCF-7 Cell, HELA Cell, CEM Cell, SMMC Cell, COLO320 Cell. IHC: Rat Brain tissue, human placenta tissue, rat intestines tissue, mouse intestines tissue IHC-F: Rat Cardiac Muscle tissue. ICC/IF: SK-OV-3 cell, Hela cell.

This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: API5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: API5
• Gene Alias: AAC11; AAC-11; AI196452; antiapoptosis clone 11 protein; API5; API-5; Apoptosis inhibitor 5; cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; fibroblast growth factor 2-interacting factor 2; FIF; FIF C1; MIG8; migration-inducing protein MIG8; Protein XAGL
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11800, 362170, 8539
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 5 mg BSA and 0.05 mg sodium azide, 0.05 mg thimerosal
• Gene Accession No.: O35841, Q9BZZ5
• Gene Symbols: API5
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Apoptosis inhibitor 5 (487-504aa KYSSNLGNFNYERSLQGK) (b).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG