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Invitrogen™ API5 Polyclonal Antibody
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Catalog No. PIPA578793
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100 μg
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PIPA578793 100 μg
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Catalog No. PIPA578793 Supplier Invitrogen™ Supplier No. PA578793
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Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Cardiac Muscle TissueRat Brain Tissue, Rat Testis Tissue, Rat Placenta Tissue, MCF-7 Cell, HELA Cell, CEM Cell, SMMC Cell, COLO320 Cell. IHC: Rat Brain tissue, human placenta tissue, rat intestines tissue, mouse intestines tissue IHC-F: Rat Cardiac Muscle tissue. ICC/IF: SK-OV-3 cell, Hela cell.

This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen API5
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene API5
Gene Accession No. O35841, Q9BZZ5
Gene Alias AAC11; AAC-11; AI196452; antiapoptosis clone 11 protein; API5; API-5; Apoptosis inhibitor 5; cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; fibroblast growth factor 2-interacting factor 2; FIF; FIF C1; MIG8; migration-inducing protein MIG8; Protein XAGL
Gene Symbols API5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Apoptosis inhibitor 5 (487-504aa KYSSNLGNFNYERSLQGK) (b).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11800, 362170, 8539
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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