Invitrogen™ API5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101286

Catalog No. PIPA5101286

Description

Antibody detects endogenous levels of total API-5.

This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: API5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: API5
• Gene Alias: AAC11; AAC-11; AI196452; antiapoptosis clone 11 protein; API5; API-5; Apoptosis inhibitor 5; cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; fibroblast growth factor 2-interacting factor 2; FIF; FIF C1; MIG8; migration-inducing protein MIG8; Protein XAGL
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11800, 8539
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O35841, Q9BZZ5
• Gene Symbols: API5
• Immunogen: A synthesized peptide derived from human API5(Accession Q9BZZ5), corresponding to amino acid residues L428-R478.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov