Invitrogen™ APLP1 Monoclonal Antibody (354008)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524099

Catalog No. PIMA524099

Description

In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse APLP-1 is observed and no cross-reactivity with recombinant human APLP-2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: APLP1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P51693
• Gene Symbols: APLP1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human APLP-1 Gln34-Glu580 (predicted).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry
• Clone: 354008
• Conjugate: Unconjugated
• Gene: APLP1
• Gene Alias: amyloid beta (A4) precursor-like protein 1; amyloid beta precursor like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; APLP; APLP 1; APLP1; APLP-1; Aplp1_retired; APLPAPLP-1; C30; RGD1561211
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 333
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized