Invitrogen™ APLP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120825

Catalog No. PIPA5120825

Description

Positive test controls include: C6, Mouse brain, Rat brain. The target is usually found in the following locations: Cell membrane, Cytoplasm, Single-pass type I membrane protein. Immunogen sequence: NPHLAQELRP QIQELLHSEH LGPSELEAPA PGGSSEDKGG LQPPDSKDDT PMTLPKGSTE QDAASPEKEK MNPLEQYERK VNASVPRGFP FHSSEIQRDE LAPAGTGVSR E.

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: APLP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APLP1
• Gene Alias: amyloid beta (A4) precursor-like protein 1; amyloid beta precursor like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; APLP; APLP 1; APLP1; APLP-1; Aplp1_retired; APLPAPLP-1; C30; RGD1561211
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11803, 333, 502317
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.99 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P51693, Q03157
• Gene Symbols: APLP1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 470-580 of human APLP1 (NP_0051571).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG