Invitrogen™ APLP1 Polyclonal Antibody

Catalog No.	Quantity
PIPA556020	100 μL

Catalog No. PIPA556020 Supplier Invitrogen™ Supplier No. PA556020

Description

Rabbit Polyclonal Antibody

Immunogen sequence: HLAQELRPQI QELLHSEHLG PSELEAPAPG GSSEDKGGLQ PPDSKDDTPM TLPKGSTEQD AASPEKEKMN PLEQYERKVN ASVPRGFPFH SSEIQRDELA PAGTGVSLGA PHR Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 70%.

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: APLP1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: APLP1
• Gene Accession No.: P51693
• Gene Alias: amyloid beta (A4) precursor-like protein 1; amyloid beta precursor like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; APLP; APLP 1; APLP1; APLP-1; Aplp1_retired; APLPAPLP-1; C30; RGD1561211
• Gene Symbols: APLP1
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human APLP1. Recombinant protein control fragment (Product #RP-102552).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 333
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG