APOBR Monoclonal Antibody (OTI3D11), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA807088

Catalog No. 50-168-1390

Description

Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remt lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

Specifications

• Antigen: APOBR
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q0VD83
• Gene Symbols: APOBR
• Immunogen: Human recombit protein fragment corresponding to amino acids 780-1088 of human APOBR produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI3D11
• Conjugate: Unconjugated
• Gene: APOBR
• Gene Alias: APOB100R, APOB48R
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55911
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid