Invitrogen™ ApoC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114865

Catalog No. PIPA5114865

Description

Antibody detects endogenous levels of total APOC3.

Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Specifications

• Antigen: ApoC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APOC3
• Gene Alias: Apoc3; APOCIII; Apo-CIII; apoC-III; Apolipoprotein; Apolipoprotein C3; apolipoprotein C-3; apolipoprotein C-III; HALP2; MGC150353
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11814, 24207, 345
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P02656, P06759, P33622
• Gene Symbols: APOC3
• Immunogen: A synthesized peptide derived from human APOC3(Accession P02656), corresponding to amino acid residues K44-T94.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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