Invitrogen™ APOC4 Polyclonal Antibody

Catalog No.	Quantity
PA550551	100 μL

Catalog No. PA550551 Supplier Invitrogen™ Supplier No. PA550551

Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total Apolipoprotein CIV / APOC4 protein.

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (5-7). The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8). The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10).

Specifications

• Antigen: APOC4
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: APOC4
• Gene Accession No.: P55056
• Gene Alias: A4; AAA; ABETA; Abeta40; Abeta42; ABPP; Acl; AD1; AICD-50; AICD-57; AICD-59; Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; APOC4; Apo-CIV; apoC-IV; Apolipoprotein; apolipoprotein C2 linked; apolipoprotein C2-linked; Apolipoprotein C4; apolipoprotein CIV; Apolipoprotein C-IV; apolipoprotein E-linked; APP; APPI; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; ECL; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); peptidase nexin-II; PN2; PN-II; PreA4; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
• Gene Symbols: APOC4
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to residues near the C terminal of human apolipoprotein C-IV.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 346
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov