Invitrogen™ Apolipoprotein C1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111339

Catalog No. PIPA5111339

Description

Immunogen sequence: PDVSSALDKL KEFGNTLEDK ARELISRIKQ SELSAKMREW FSETFQKVKE.

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues. The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase. The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver.

Specifications

• Antigen: Apolipoprotein C1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APOC1
• Gene Alias: ALPCI; Apoc1; Apo-CI; ApoC-I; Apo-CIB; ApoC-IB; apolipoprotein C1; Apolipoprotein C-I; apolipoprotein C-I variant I; apolipoprotein C-I variant II; Liver regeneration-related protein LRRG04; LRRG04; Truncated apolipoprotein C-I
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 341
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P02654
• Gene Symbols: APOC1
• Immunogen: Recombinant Protein corresonding to Human Apolipoprotein C1. Recombinant protein control fragment (Product #RP-101269).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov