Invitrogen™ Apolipoprotein L3 Polyclonal Antibody

Catalog No.	Quantity
PIPA565168	100 μL

Catalog No. PIPA565168 Supplier Invitrogen™ Supplier No. PA565168

Description

Rabbit Polyclonal Antibody

Immunogen sequence: TFTFPFGFQGI SQRLENVSGY YADARLEVGS TQLRTAGSCS HSFKRSFLEK KRFTEEATKY FRERVSPVHL QILL Highest antigen sequence identity to the following orthologs - mouse 29%, rat 25%.

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL1-6, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1-13.1 within a 127,000 bp region. apoL2 and apoL3 may allow the binding of lipids to organelles or may be involved in the movement of lipids in the cytoplasm. apoL2 localizes to the cytoplasm and is widely expressed, with the highest levels observed in the lung, thymus, pancreas, placenta, adult brain and prostate. The apoL2 protein is also detected in the spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver. apoL3 also localizes to the cytoplasm and is widely expressed, with highest levels detected in the prostate, lung and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland. Lower levels of apoL3 are observed in the brain, heart, fetal liver, pancreas and testis.

Specifications

• Antigen: Apolipoprotein L3
• Applications: Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: APOL3
• Gene Accession No.: O95236
• Gene Alias: APOL3; APOLIII; ApoL-III; apolipoprotein L, 3; Apolipoprotein L3; apolipoprotein L-III; CG12_1; CG121; CG12-1; OTTHUMP00000028913; TNF-inducible protein CG12-1
• Gene Symbols: APOL3
• Host Species: Rabbit
• Immunogen: Recombinant Human Apolipoprotein L3. Recombinant protein control fragment (Product #RP-105919).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 80833
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG