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Apollon/BIRC6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983344
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50-198-3344 100 μL
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Catalog No. 50-198-3344 Supplier Bioss Supplier No. BS1489R
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Description

Rabbit Polyclonal Antibody

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.

Specifications

Antigen Apollon/BIRC6
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene BIRC6
Gene Accession No. Q9NR09
Gene Alias A430032G04Rik; A430040A19Rik; AA501170; APOLLON; baculoviral IAP repeat containing 6; baculoviral IAP repeat-containing 6; Baculoviral IAP repeat-containing protein 6; baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; accccbaculoviral IAP repeat-containing 6; BIR repeat-containing ubiquitin-conjugating enzyme; BIRC6; BRUCE; D630005A10Rik; Kiaa1289; mKIAA1289; RING-type E3 ubiquitin transferase BIRC6; Ubiquitin-conjugating BIR domain enzyme apollon; ubiquitin-conjugating BIR-domain enzyme apollon
Gene Symbols BIRC6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Apollon.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57448
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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