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  5. Tocris Bioscience™ Apoptosis Activator 2

Tocris Bioscience™ Apoptosis Activator 2
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Catalog No. 209850
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50 mg
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Catalog No. Quantity
20-985-0 50 mg
20-981-0 10 mg
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Catalog No. 20-985-0 Supplier Tocris Bioscience™ Supplier No. 2098/50
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Description

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM).

Chemical Identifiers

CAS 79183-19-0
Molecular Formula C15H9Cl2NO2

Specifications

Quantity 50 mg
Formula Weight 306.14
Purity >99%
Molecular Weight (g/mol) 306.14
Chemical Name or Material Apoptosis Activator 2

Safety and Handling

Recommended Storage Store at Room Temperature
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