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APPBP1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982291
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100 μL
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50-198-2291 100 μL
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Catalog No. 50-198-2291 Supplier Bioss Supplier No. BS12503R
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Rabbit Polyclonal Antibody

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer′s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen APPBP1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NAE1
Gene Accession No. Q13564
Gene Alias 59kDa; A-116A10.1; amyloid beta precursor protein binding protein 1, 59kDa; Amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; Amyloid protein-binding protein 1; Appbp1; APP-BP1; HPP1; NAE1; NEDD8 activating enzyme E1 subunit 1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; protooncogene protein 1; Proto-oncogene protein 1; ula-1
Gene Symbols NAE1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human APPBP1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8883
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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