Invitrogen™ APPL1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518643

Catalog No. PIPA518643

Description

This antibody is predicted to react with bovine, canine, human, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signaling and insulin signaling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Specifications

• Antigen: APPL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APPL1
• Gene Alias: 2900057D21Rik; 7330406P05Rik; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein APPL like; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; AI585782; AKT2 interactor; APPL; Appl1; AW209077; BB022931; C88264; DCC-interacting protein 13-alpha; DIP13; DIP13 alpha; DIP13A; DIP13alpha; dip13-alpha; Kiaa1428; MODY14; RGD1309388; signaling adaptor protein DIP13alpha
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 26060
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UKG1
• Gene Symbols: APPL1
• Immunogen: Synthetic peptide sequence (NRYSRLSKKRENDK) corresponding to the internal amino acids of APPL1 (aa 145-159).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG