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Invitrogen™ APRIL Monoclonal Antibody (Aprily-1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA125839

Catalog No. PIMA125839


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Description

Description

MA1-25839 will not react with mouse.

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

APRIL
Monoclonal
1 mg/mL
PBS with 0.02% sodium azide
O75888
TNFSF13
Recombinant fragment corresponding to residues 93-233 of human APRIL, expressed in bacteria.
50 μg
Primary
Human
Antibody
IgG1
Flow Cytometry, Western Blot
Aprily-1
Unconjugated
TNFSF13
2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
Mouse
Purified
RUO
8741
4°C
Liquid
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