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Invitrogen™ APRIL Polyclonal Antibody
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Catalog No. PIPA5142475
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100 μg
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PIPA5142475 100 μg
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Catalog No. PIPA5142475 Supplier Invitrogen™ Supplier No. PA5142475
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize all isoforms (alpha, beta, gamma: NP_003799.1; NP_742084.1; NP_742085.1). This antibody also cross-reacts with human, mouse and dog TNFSF12-TNFSF13 protein. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APRIL
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene TNFSF13
Gene Accession No. O75888
Gene Alias 2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
Gene Symbols TNFSF13
Host Species Goat
Immunogen Peptide with sequence C-PRARAKLNLSPHGT.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8741
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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