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Invitrogen™ AQR Polyclonal Antibody
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Catalog No. PIPA570646
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100 μL
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PIPA570646 100 μL
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Catalog No. PIPA570646 Supplier Invitrogen™ Supplier No. PA570646
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Horse: 79%; Human: 100%.

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346). Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis (PubMed:16949364). Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly (PubMed:16949364). May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing (PubMed:16949364). Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro) (PubMed:25599396). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen AQR
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene AQR
Gene Accession No. O60306
Gene Alias Aqr; aquarius; aquarius homolog; aquarius intron-binding spliceosomal factor; AW495846; fSAP164; functional spliceosome-associated protein 164; IBP160; intron-binding protein aquarius; intron-binding protein of 160 kDa; Kiaa0560; mKIAA0560; RNA helicase aquarius
Gene Symbols AQR
Host Species Rabbit
Immunogen synthetic peptide directed towards the C-terminal region of human AQR.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9716
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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