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Invitrogen™ Aquaporin 2 Monoclonal Antibody (5B6B12)
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Catalog No. PIMA531631
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100 μL
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Catalog No. Quantity
PIMA531631 100 μL
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Catalog No. PIMA531631 Supplier Invitrogen™ Supplier No. MA531631
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Mouse Monoclonal Antibody

MA5-31631 has been tested in indirect ELISA.

Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans. A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells. Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aquaporin 2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 5B6B12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Aqp2
Gene Accession No. P41181
Gene Alias ADH water channel; AQP 2; AQP CD; Aqp2; AQP-2; AQPCD; AQP-CD; aquaporin 2; aquaporin 2 (collecting duct); Aquaporin CD; Aquaporin2; aquaporin-2; Aquaporin-CD; Aquaporine 2; collecting duct water channel protein; cph; jpk; MGC34501; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH CD; WCHCD; WCH-CD
Gene Symbols Aqp2
Host Species Mouse
Immunogen Purified recombinant fragment of human AQP2 (AA: 149-271) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 359
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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