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Invitrogen™ Aquaporin 2 Monoclonal Antibody (5B6B12)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA531631
Description
MA5-31631 has been tested in indirect ELISA.
Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans. A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells. Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking.
Specifications
Aquaporin 2 | |
Monoclonal | |
1 mg/mL | |
PBS with 0.05% sodium azide | |
P41181 | |
Aqp2 | |
Purified recombinant fragment of human AQP2 (AA: 149-271) expressed in E. coli. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
ELISA, Western Blot | |
5B6B12 | |
Unconjugated | |
Aqp2 | |
ADH water channel; AQP 2; AQP CD; Aqp2; AQP-2; AQPCD; AQP-CD; aquaporin 2; aquaporin 2 (collecting duct); Aquaporin CD; Aquaporin2; aquaporin-2; Aquaporin-CD; Aquaporine 2; collecting duct water channel protein; cph; jpk; MGC34501; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH CD; WCHCD; WCH-CD | |
Mouse | |
Protein G | |
RUO | |
359 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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