Invitrogen™ Aquaporin 3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577840

Catalog No. PIPA577840

Description

0.5 μg/mL of PA5-77840 was sufficient for detection of aquaporin 3 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 31.5kDa. May detect larger glycosylated bands approximately 35-50kDa.

AQP3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.

Specifications

• Antigen: Aquaporin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AQP3
• Gene Alias: 31.4 kDa water channel protein; AQP 3; AQP-2; AQP3; AQP-3; Aquaglyceroporin-3; aquaporin 3; aquaporin 3 (GIL blood group); aquaporin 3 (Gill blood group); Aquaporin3; aquaporin-3; GIL; Gill blood group
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11828, 360, 65133
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P47862, Q8R2N1, Q92482
• Gene Symbols: AQP3
• Immunogen: Produced against the C-terminal peptide (Sequence N-CHLEQPPPSTEAENVKLAHMKHKEQI) of rat aquaporin 3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG