Invitrogen™ Aquaporin 4 Monoclonal Antibody (C9)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541556	Invitrogen™ MA541556	200 μL
PIMA543952	Invitrogen™ MA543952	20 μL

Description

Aquaporin 4 Monoclonal Antibody for Western Blot, IHC (P)

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.

Specifications

• Antigen: Aquaporin 4
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P55087
• Gene ID (Entrez): 361
• Immunogen: Recombinant protein Aquaporin 4. The antigen corresponds to amino acid range 178-317 of the target protein.
• Product Type: Antibody

• Clone: C9
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG2a κ
• Target Species: Human
• Gene: AQP4
• Gene Alias: Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4
• Gene Symbols: AQP4
• Primary or Secondary: Primary
• Purification Method: Protein A/G