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Invitrogen™ Aquaporin 4 Polyclonal Antibody
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Catalog No. PIPA578812
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100 μg
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Catalog No. Quantity
PIPA578812 100 μg
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Catalog No. PIPA578812 Supplier Invitrogen™ Supplier No. PA578812
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat brain tissue, rat brain tissue, mouse brain tissue, mouse brain tissue. IHC: human lung cancer tissue, mouse brain tissue, rat brain tissue IHC-F: Mouse Brain tissue, Rat Brain tissue.

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aquaporin 4
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene AQP4
Gene Accession No. P47863, P55087, P55088
Gene Alias Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4
Gene Symbols AQP4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 4 (295-323aa KPGVVHVIDVDRGEEKKGKDQSGEVLSSV).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11829, 25293, 361
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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