Invitrogen™ Aquaporin 5 Polyclonal Antibody

Catalog No.	Quantity
PIPA599403	100 μL

Catalog No. PIPA599403 Supplier Invitrogen™ Supplier No. PA599403

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total AQP5.

Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

Specifications

• Antigen: Aquaporin 5
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: AQP5
• Gene Accession No.: P47864, P55064
• Gene Alias: AQP 5; Aqp5; AQP-5; aquaporin 5; Aquaporin5; aquaporin-5; PPKB
• Gene Symbols: AQP5
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human AQP5(Accession P55064), corresponding to amino acid residues Y223-R265.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 25241, 362
• Target Species: Human, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG