Invitrogen™ Aquaporin 5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578814

Catalog No. PIPA578814

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Lung Tissue, Rat Testis Tissue. IHC: Rat Lung Tissue.

Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

Specifications

• Antigen: Aquaporin 5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AQP5
• Gene Alias: AQP 5; Aqp5; AQP-5; aquaporin 5; Aquaporin5; aquaporin-5; PPKB
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11830, 25241
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P47864, Q9WTY4
• Gene Symbols: AQP5
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse AQP5 (246-265aa EEDWEDHREERKKTIELTAH).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG