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Invitrogen™ ARAP1 Monoclonal Antibody (ARAP1-2)
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Catalog No. MA119728
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Quantity:
100 μg
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Catalog No. Quantity
MA119728 100 μg
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Catalog No. MA119728 Supplier Invitrogen™ Supplier No. MA119728
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Description

Mouse Monoclonal Antibody

This antibody reacts with C-terminal part of ARAP1 (intracellular epitope), a 160 kDa adaptor protein.

ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeat. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
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Specifications

Antigen ARAP1
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone ARAP1-2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene Arap1
Gene Accession No. Q96P48
Gene Alias 2410002L19Rik; arap1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1; ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1; centaurin, delta 2; centaurin-delta-2; Centd2; cnt-d2; Kiaa0782; mKIAA0782
Gene Symbols Arap1
Host Species Mouse
Immunogen His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116985
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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