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Invitrogen™ ARAP1 Polyclonal Antibody
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Catalog No. PA550604
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100 μL
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PA550604 100 μL
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Catalog No. PA550604 Supplier Invitrogen™ Supplier No. PA550604
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total ARAP1 protein.

ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeat. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARAP1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 2.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Arap1
Gene Accession No. Q96P48
Gene Alias 2410002L19Rik; arap1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1; ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1; centaurin, delta 2; centaurin-delta-2; Centd2; cnt-d2; Kiaa0782; mKIAA0782
Gene Symbols Arap1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from internal residues of human ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116985
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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