Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA587923

Invitrogen™ ARAP1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA587923
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA587923 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA587923 Supplier Invitrogen™ Supplier No. PA587923
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: SVDEEELRKQ REEITAIVKM RVAGTASGTQ HAGDFICTVY LEEKKAETEQ HIKVPASMTA EELTLEILDR RNVGIREKDY WTCFEVNERE EAERPLHFAE KVLPILHGLG TDSHLVVKKH QAMEAMLLYL ASRVGDTKHG MMKFREDRSL LGLGLPSGGF HDRYFILNSS CLRLYKEVRS HRPEKEWPIK SLKVYLGVKK KLRPPTCWGF TVVHETEKHE KQQWYLCCDT QMELREWFAT FLFVQHDGLV WPSEPSRVSR AVPEVRLGSV SLIPLRGSEN EMRRSVAAFT ADPLSLLRNV; Positive Samples: 293T, LO2, HeLa, Mouse liver, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Golgi apparatus, Golgi stack membrane, Peripheral membrane protein.

ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeat. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARAP1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Arap1
Gene Accession No. Q4LDD4
Gene Alias 2410002L19Rik; arap1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1; ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1; centaurin, delta 2; centaurin-delta-2; Centd2; cnt-d2; Kiaa0782; mKIAA0782
Gene Symbols Arap1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 834-1133 of human ARAP1 (NP_0011286621).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361617, 69710
Target Species Mouse, Rat, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.