Invitrogen™ ARAP1 Polyclonal Antibody

Catalog No.	Quantity
PIPA5142073	100 μg

Catalog No. PIPA5142073 Supplier Invitrogen™ Supplier No. PA5142073

Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognise isoform a (NP_056057.2), isoform c (NP_001035207.1) and isoform d (NP_001128662.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeat. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.

Specifications

• Antigen: ARAP1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: Arap1
• Gene Accession No.: Q4LDD4, Q96P48
• Gene Alias: 2410002L19Rik; arap1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1; ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1; centaurin, delta 2; centaurin-delta-2; Centd2; cnt-d2; Kiaa0782; mKIAA0782
• Gene Symbols: Arap1
• Host Species: Goat
• Immunogen: Peptide with sequence C-AFTADPLSLLRNV.
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 116985, 69710
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG