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Invitrogen™ Arfaptin 2 Polyclonal Antibody
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Catalog No. PIPA528012
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100 μL
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PIPA528012 100 μL
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Catalog No. PIPA528012 Supplier Invitrogen™ Supplier No. PA528012
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (99%), Rat (99%), Sheep (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Arfaptin 2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene ARFIP2
Gene Accession No. P53365
Gene Alias 2310002N04Rik; ADP ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2 (arfaptin 2); ADP-ribosylation factor-interacting protein 2; Arfaptin 2; arfaptin-2; Arfip2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR; POR1; Protein POR1
Gene Symbols ARFIP2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ARFIP2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23647
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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