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Invitrogen™ ARFGAP1 Polyclonal Antibody
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Catalog No. PIPA5101408
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PIPA5101408 100 μL
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Catalog No. PIPA5101408 Supplier Invitrogen™ Supplier No. PA5101408
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ARFGAP1.

ArfGAP1 is a 406 amino acid containing regulatory protein with an Arf-GAP domain known to be involved in the activation of the GTPase activity of ADP ribosylation factor (ARF). ArfGAP1, a GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), promotes the hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles thus playing an important role in membrane trafficking and/or vesicle transport. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported. Ubiquitous expression of ArfGAP1 is seen in most tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARFGAP1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ARFGAP1
Gene Accession No. Q62848, Q8N6T3, Q9EPJ9
Gene Alias ADP ribosylation factor GTPase activating protein 1; ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase-activating protein 1; AI115377; ARF GAP 1; Arf GAP1; ARF1 GAP; ARF1-directed GTPase-activating protein; Arf1gap; ARFGAP1; EGK_02194; GAP protein; HRIHFB2281; RP11-261N11.1
Gene Symbols ARFGAP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ARFGAP1(Accession Q8N6T3), corresponding to amino acid residues D303-D353.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 228998, 246310, 55738
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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