ARFGAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8844	Proteintech Group Inc 135711AP150UL	150 μL

Description

ArfGAP1 is a 406 amino acid containing regulatory protein with an Arf-GAP domain known to be involved in the activation of the GTPase activity of ADP ribosylation factor (ARF). ArfGAP1, a GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), promotes the hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles thus playing an important role in membrane trafficking and/or vesicle transport. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported. Ubiquitous expression of ArfGAP1 is seen in most tissues.

Specifications

• Antigen: ARFGAP1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q62848, Q8N6T3, Q9EPJ9
• Gene ID (Entrez): 228998, 246310, 55738
• Immunogen: ARFGAP1 Fusion Protein Ag4468
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ARFGAP1

• Concentration: 0.41 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: ARF GAP 1, ARF1 GAP, ARF1GAP, ARFGAP1, HRIHFB2281
• Gene Symbols: ARFGAP1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody