Invitrogen™ ARFGAP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530515

Catalog No. PIPA530515

Description

Recommended positive controls: NT2D1, IMR32, U87-MG. Predicted reactivity: Human (99%), Rhesus Monkey (94%), Chimpanzee (97%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

Specifications

• Antigen: ARFGAP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARFGAP3
• Gene Alias: 0610009H19Rik; 1810004P07Rik; 1810035F16Rik; 9130416J18Rik; ADP ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3; ARF1GAP; ARFGAP1; ARFGAP3; arfgap3 {ECO:0000250; FLJ45618; HRIHFB2281; MGC39924; OTTHUMP00000028526; RP11-261N11.1; RP1-47A17.3; UniProtKB:Q9NP61}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26286
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9NP61
• Gene Symbols: ARFGAP3
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 211 and 483 of Human ARFGAP3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG