Invitrogen™ ARFGAP3 Polyclonal Antibody

Catalog No.	Quantity
PIPA5109406	100 μL

Catalog No. PIPA5109406 Supplier Invitrogen™ Supplier No. PA5109406

Description

Rabbit Polyclonal Antibody

Immunogen sequence: KPNQAKKGLG AKKGSLGAQK LANTCFNEIE KQAQAADKMK EQEDLAKVVS KEESIVSSLR LAYKDLEIQM KKDEKMNISG KKNVDSDRLG MGFGNCRSVI SHSVTSDMQT IEQESPIMAK PRKKYNDDSD DSYFTSSSSY FDEPVELRSS SFSSWDDSSD SYWKKETSKD TETVLKTTGY SDRPTARRKP DYEPVENTDE AQKKFGNVKA ISSDMYFGRQ SQADYETRAR LERLSASSSI SSADLFEEPR KQPAGNYSLS SVLPNAPDMA QFKQGVRSVA GKLSVFANGV VTSIQDRYGS.

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

Specifications

• Antigen: ARFGAP3
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.578 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ARFGAP3
• Gene Accession No.: Q9D8S3, Q9NP61
• Gene Alias: 0610009H19Rik; 1810004P07Rik; 1810035F16Rik; 9130416J18Rik; ADP ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3; ARF1GAP; ARFGAP1; ARFGAP3; arfgap3 {ECO:0000250; FLJ45618; HRIHFB2281; MGC39924; OTTHUMP00000028526; RP11-261N11.1; RP1-47A17.3; UniProtKB:Q9NP61}
• Gene Symbols: ARFGAP3
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 217-516 of human ARFGAP3 (NP_055385.3).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26286, 66251
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG