ARFGAP3 Polyclonal Antibody, Rockland™

Catalog No.	Quantity
50-199-0129	100 μL
50-199-0130	25 μL

Catalog No. 50-199-0129 Supplier Rockland Immunochemicals Supplier No. 100401H46

Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. The antibody detects ArfGAP3 in cell lysates. A BLAST analysis was used to suggest cross reactivity with human, monkey, and orangutan for ArfGAP3. Cross-reactivity with AfGAP3 from other sources have not been determined.

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

Specifications

• Antigen: ARFGAP3
• Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 70 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene: ARFGAP3
• Gene Accession No.: Q9NP61
• Gene Alias: 0610009H19Rik; 1810004P07Rik; 1810035F16Rik; 9130416J18Rik; ADP ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3; ARF1GAP; ARFGAP1; Arfgap3; arfgap3 {ECO:0000250; FLJ45618; HRIHFB2281; MGC39924; OTTHUMP00000028526; RP11-261N11.1; RP1-47A17.3; UniProtKB:Q9NP61}
• Gene Symbols: ARFGAP3
• Host Species: Rabbit
• Immunogen: This whole rabbit serum was prepared by repeated immunizations with a truncated recombinant sequence of ArfGAP3 fused to GST.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26286
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid